ROLE OF PROGNOSTIC FACTORS IN THE DEVELOPMENT OF CENTRIC BREAST CANCER RECURRENCE
https://doi.org/10.17650/1994-4098-2009-0-3-4-11-14
Abstract
The purpose of the study was to define the factors influencing the development of a recurrence depending on the volume of surgical intervention and to investigate the possibility of performing organ-saving surgery (OSS) for centric breast cancer.
The study used the clinical findings of 200 patients treated at the Department of Radiosurgery, N.N. Blokhin Russian Cancer Research Center in 1996 to 2006. According to the volume of surgical intervention, the patients were divided into 2 groups: 1) 106 patients who had undergone radical mastectomy; 2) 94 patients who had undergone radical resection. According to our data, the disease progressed in 32 (16%) cases. There were 12 local recurrences: in 8 (7.5%) and 4 (4.2%) cases after radical mastectomy and radical resection, respec- tively. The findings suggest that OSS may be performed after carefully patient selection, with all contraindications being kept in mind.
About the Authors
E. A. Sotskova
N.N. Blokhin Russian Cancer Research Cancer, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
A. V. Petrovsky
N.N. Blokhin Russian Cancer Research Cancer, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
I. V. Poddubnaya
N.N. Blokhin Russian Cancer Research Cancer, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
M. I. Nechushkin
N.N. Blokhin Russian Cancer Research Cancer, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
References
1. Вишнякова В.В. Эффективность экономных операций при раке молочной железы. Вопр онкол 1990;36(5):540—4.
2. Летягин В.П. Современные тенденции в лечении первичного рака молочной железы. Вестн ВОНЦ АМН СССР 1990;(1):40—2.
3. Портной С.М., Лактионов К.П., Барканов А.И. и др. Органосохраняющие операции при раке молочной железы I—II стадии. Материалы I съезда онкологов стран СНГ. М., 1996.
4. Семиглазов В.Ф., Веснин А.Г., Мо- исеенко В.М. Минимальный рак молочной железы. Спб.: Гиппократ, 1992.
5. Fisher B., Slack N.H., Cavanaugh P.J. Postoperative radiotherapy in the treatment of breast cancer: results of the NSABP clin- ical trial. Ann Surg 1970;172(4):711—32.
6. Veronesi U., Luini A., Del Vecchio M. et al. Radiotherapy after breast-preserv- ing surgery in woman with localized can- cer of the breast. N Engl J Med 1993;328:1587—91.
7. Путырский Л.А. Рак молочной железы. Минск, 1998.
8. Rutgers E.J.Th. for the EUSOMA Consensus Group. Qualiti assurance guidelines for surgery. European guide- lines for guality assurance in breast can- cer screening and diagnosis, 2006.
9. Goldhirsch A., Wood W., Gelber R. et al. Progress and promis: highlights of the international expert consensus on the pri- mari therapy of early breast cancer 2007. Ann Oncol 2007;18(7):1133—44.
10. Fowble B.L., Solin L.J., Schultz D.J. Breast recurrence and survival related to primary tumor location in patients under- going conservative surgery and radiation for early stage breast cancer. Int J Radiat Oncol Biol Phys 1992;23(5):933—9.
Review
For citations:
Sotskova E.A., Petrovsky A.V., Poddubnaya I.V., Nechushkin M.I. ROLE OF PROGNOSTIC FACTORS IN THE DEVELOPMENT OF CENTRIC BREAST CANCER RECURRENCE. Tumors of female reproductive system. 2009;(3-4):11-14. (In Russ.) https://doi.org/10.17650/1994-4098-2009-0-3-4-11-14
Views:
562
Email this article 