MOLECULAR BIOLOGICAL AND RADIOLOGICAL TECHNOLOGIES IN THE COMPLEX DIAGNOSIS OF AUXILLARY PATHOLOGY

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Abstract

Introduction. A diversity of axillary pathologies was a prerequisite for the development of a new differential approach to diagnosing such conditions. There are new technologies (pre- and intraoperative radionuclide studies, molecular genetic techniques), that have shown themselves, along with classical methods (physical examination, mammography, X-ray and ultrasound studies).
Materials and methods. The subject of the analysis is the results of a comprehensive examination of 502 women aged 22 to 84 years. Different groups were comprehensively examined using both X-ray, ultrasound, radionuclide, and molecular genetic (polymerase chain reaction) studies.
Results. The molecular genetic and cytological studies could provide the actual results in 95 and 84% of cases, respectively; but a com- prehensive clinical study and X-ray ultrasound computed tomography could yield them in marginal metastases in only 65.3%.
Conclusion. The authors have proposed the optimal diagnostic algorithm for examination in the ambulatory-outpatient network and specialized institutions.

About the authors

N. I. Rozhkova

Russian Radiology Research Center, Moscow

Russian Federation

V. K. Bozhenko

Russian Radiology Research Center, Moscow

Author for correspondence.
Email: vbojenko@mail.ru
Russian Federation

D. K. Fomin

Russian Radiology Research Center, Moscow

Russian Federation

A. I. Ploshnitsa

Russian Radiology Research Center, Moscow

Russian Federation

A. A. Tashchan

Russian Radiology Research Center, Moscow

Russian Federation

E. A. Kudinova

Russian Radiology Research Center, Moscow

Russian Federation

E. F. Vaskevich

Russian Radiology Research Center, Moscow

Russian Federation

M. L. Mazo

Russian Radiology Research Center, Moscow

Russian Federation

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