Email this article CLINICAL AND IMMUNOLOGIC IMPORTANCE OF MDR1/PGP 170 EXPRESSION IN PATIENTS WITH BREAST CANCER
- Authors: Yengay D.A.1,2, Poddubnaya I.V.1,2, Tupitsin N.N.1,2, Mechetner Y.B.1,2
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Affiliations:
- State Institution N.N. Blokhin Russian Cancer Research Center of Russian Academy of Medical Sciences, Moscow
- Department of oncology of Russian Medical Academy of Post-Graduate Education, Moscow
- Issue: No 3 (2008)
- Pages: 41-43
- Section: MAMMOLOGY. NEW TECHNOLOGIES
- Published: 16.08.2008
- URL: https://ojrs.abvpress.ru/ojrs/article/view/362
- DOI: https://doi.org/10.17650/1994-4098-2008-0-3-41-43
- ID: 362
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Abstract
Clinical, morphologic and immunohistochemical data of 51 patients with stage T2N1-3M0 breast cancer treated in the N.N. Blokhin Russian Cancer Research Center of Russian Academy of Medical Sciences in 2002 was analyzed. Expression of Pgp 170 was found in 19 patients. Relationship between immunophenotype of stage T2N1-3M0 breast cancer cells and main clinical and morphologic fea- tures, treatment provided and expression of multiple drug resistance gene MDR1.
About the authors
D. A. Yengay
State Institution N.N. Blokhin Russian Cancer Research Center of Russian Academy of Medical Sciences, Moscow; Department of oncology of Russian Medical Academy of Post-Graduate Education, Moscow
Author for correspondence.
Russian Federation
I. V. Poddubnaya
State Institution N.N. Blokhin Russian Cancer Research Center of Russian Academy of Medical Sciences, Moscow; Department of oncology of Russian Medical Academy of Post-Graduate Education, MoscowRussian Federation
N. N. Tupitsin
State Institution N.N. Blokhin Russian Cancer Research Center of Russian Academy of Medical Sciences, Moscow; Department of oncology of Russian Medical Academy of Post-Graduate Education, MoscowRussian Federation
Ye. B. Mechetner
State Institution N.N. Blokhin Russian Cancer Research Center of Russian Academy of Medical Sciences, Moscow; Department of oncology of Russian Medical Academy of Post-Graduate Education, MoscowRussian Federation
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