INDOL-3-CARBINOL IN THE TREATMENT OF BENIGN BREAST DISORDERS
https://doi.org/10.17650/1994-4098-2008-0-3-50-54
Abstract
123 patients with various forms of fibrocystic mastopathy (n=114) and fibroadenoma of mammry gland (n=9) were enrolled into the study. Indol-3-carbinol (indinol, Close corporation «Mirax-Pharma») was administered in the dose of 300—400 mg per day for 3—6 months. Disappearance of complaints to pain was observed in 35% of patients after 3 months of therapy and in 63% — after 6 months of therapy. Objective signs of fibrocystic mastopathy completely regressed in 9% of patients after 3 months of therapy and in 16% — after 6 month of therapy. Overall considerable improvement of condition or complete cure was seen in 55% of patients after 3 month of treatment and in 92% — after 6 months of therapy. Thus, indinol is highly effective and safe agent for treatment of different types of mastopathy.
About the Authors
E. T. Zulkarnayeva
Republic clinical oncology dispensary
Russian Federation
Russian Federation
R. H. Hakimova
Republic clinical oncology dispensary
Russian Federation
Russian Federation
Ye. A. Lapan
Municipal policlinic No43
Russian Federation
Russian Federation
I. L. Blagodetelev
oliclinic of Municipal clinical hospital No21, Ufa
Russian Federation
Russian Federation
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Review
For citations:
Zulkarnayeva E.T., Hakimova R.H., Lapan Ye.A., Blagodetelev I.L. INDOL-3-CARBINOL IN THE TREATMENT OF BENIGN BREAST DISORDERS. Tumors of female reproductive system. 2008;(3):50-54. (In Russ.) https://doi.org/10.17650/1994-4098-2008-0-3-50-54
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