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Complex ultrasound diagnostic assessment of the results of neoadjuvant chemotherapy for locally advanced cervical cancer (Stages IIB–IIIB)

https://doi.org/10.17650/1994-4098-2015-11-2-76-81

Abstract

Background. Current complex ultrasound diagnosis using novel imaging techniques can assess, to a high accuracy, different tumor parameters during neoadjuvant chemotherapy (NCT) for locally advanced cervical cancer (CC) (Stages IIB–IIB). This assessment is very important and necessary to define further treatment policy.

Materials and methods. A total of 199 patients diagnosed with Stages IIB–IIIB CC, including 60 patients with Stage IIB (T2bN0M0), 4 with Stage IIIА (T3aN0M0), and 135 with Stage IIIВ (T2bN1M0, T3aN1M0, T3bN0–1M0) (according to the International Federation
of Gynecology and Obstetrics (FIGO) classification), who received NCT at Stage 1 of treatment, were examined. Complex ultrasound study was conducted before treatment initiation and after each NCT cycle. The therapeutic pathomorphism of a tumor was evaluated in surgically treated patients.

Results. The criteria have been determined for evaluating the efficiency of NCT for locally advanced CC, which are based on current ultrasonographic techniques including B-mode, Doppler ultrasound (power, spectral, three-dimensional ones), as well as on the results of therapeutic pathomorphism.

Conclusion. The criteria for evaluating the efficiency of NCT for CC should be based on current complex ultrasonographic techniques.

About the Authors

L. A. Ashrafyan
Russian X-ray Radiology Research Center, Ministry of Health of Russia; 86 Profsoyuznaya St., Moscow, 117997, Russia
Russian Federation


O. I. Aleshikova
Russian X-ray Radiology Research Center, Ministry of Health of Russia; 86 Profsoyuznaya St., Moscow, 117997, Russia
Russian Federation


N. A. Babaeva
Russian X-ray Radiology Research Center, Ministry of Health of Russia; 86 Profsoyuznaya St., Moscow, 117997, Russia
Russian Federation


I. B. Antonova
Russian X-ray Radiology Research Center, Ministry of Health of Russia; 86 Profsoyuznaya St., Moscow, 117997, Russia


S. V. Ivashina
Russian X-ray Radiology Research Center, Ministry of Health of Russia; 86 Profsoyuznaya St., Moscow, 117997, Russia
Russian Federation


S. L. Vashakmadze
Russian X-ray Radiology Research Center, Ministry of Health of Russia; 86 Profsoyuznaya St., Moscow, 117997, Russia
Russian Federation


A. A. Myagkova
Russian X-ray Radiology Research Center, Ministry of Health of Russia; 86 Profsoyuznaya St., Moscow, 117997, Russia
Russian Federation


T. A. Motskobili
Russian X-ray Radiology Research Center, Ministry of Health of Russia; 86 Profsoyuznaya St., Moscow, 117997, Russia
Russian Federation


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For citations:


Ashrafyan L.A., Aleshikova O.I., Babaeva N.A., Antonova I.B., Ivashina S.V., Vashakmadze S.L., Myagkova A.A., Motskobili T.A. Complex ultrasound diagnostic assessment of the results of neoadjuvant chemotherapy for locally advanced cervical cancer (Stages IIB–IIIB). Tumors of female reproductive system. 2015;11(2):76-81. (In Russ.) https://doi.org/10.17650/1994-4098-2015-11-2-76-81

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ISSN 1994-4098 (Print)
ISSN 1999-8627 (Online)