Evaluation of the scientific results of the study entitled “Opportunities for surgical treatment of patients with stage IV breast cancer” performed by Russian Society of Oncomammologists (RSOM)

A. A. Bozhok; Божок А. А.; E. E. Topuzov; Топузов Э. Э.; A. D. Zikiryakhodzhaev; Зикиряходжаев А. Д.; A. S. Sukhot’ko; Сухотько А. С.; V. A. Khaylenko; Хайленко В. А.; Yu. S. Shatova; Шатова Ю. С.; N. A. Klimov; Климов Н. А.; Р. М. Палтуев; Палтуев Р. М.

doi:10.17650/1994-4098-2016-12-4-17-24

Evaluation of the scientific results of the study entitled “Opportunities for surgical treatment of patients with stage IV breast cancer” performed by Russian Society of Oncomammologists (RSOM)

Authors: Bozhok A.A.¹^,2, Topuzov E.E.¹^,3, Zikiryakhodzhaev A.D.¹^,4, Sukhot’ko A.S.¹^,4, Khaylenko V.A.¹^,5, Shatova Y.S.¹^,6, Klimov N.A.¹^,3, Палтуев Р.М.¹^,7
Affiliations:
1. Russian Society of Oncomammologists (RSOM)
2. Saint Petersburg Clinical Research and Practical Center of Specialized Medical Care in Oncology
3. I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia
4. P.A. Herzen Moscow Oncology Research Institute – Branch of National Medical Radiological Research Center, Ministry of Health of Russia
5. N.N. Blokhin Russian Cancer Research Center, Ministry of Health of Russia
6. Rostov Research Institute of Oncology, Ministry of Health of Russia
7. N.N. Petrov Research Institute of Oncology, Ministry of Health of Russia
Issue: Vol 12, No 4 (2016)
Pages: 17-24
Section: MAMMOLOGY. ORIGINAL ARTICLE
Published: 10.11.2016
URL: https://ojrs.abvpress.ru/ojrs/article/view/520
DOI: https://doi.org/10.17650/1994-4098-2016-12-4-17-24
ID: 520

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Abstract

In 11.5 % of breast cancer patients distant metastases are detected at diagnosis. The results of treatment of 608 patients of 5 Russian oncological centers are presented. Removal of the primary tumor in case of newly diagnosed advanced breast cancer increases the mean duration of life from 23 up to 35 months (p < 0.01). Three-year overall survival increases from 47 to 65 % and 5-year survival – from 21 to 45 % (p = 0.001). The most impressive effect of surgical treatment is observed in patients with bone metastases, 1–2 metastatic lesions in one anatomical region, with positive effect after systemic treatment, high expression estrogen/progesterone receptors, possibility of attaining free surgical margins.

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breast cancer, disseminated breast cancer, surgical treatment

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Evaluation of the scientific results of the study entitled “Opportunities for surgical treatment of patients with stage IV breast cancer” performed by Russian Society of Oncomammologists (RSOM)

Full Text

Abstract

Keywords

About the authors

References

Supplementary files