Breast cancer radiology in women with hypothyroidism
https://doi.org/10.17650/1994-4098-2013-0-3-4-33-40
Abstract
The article describes the influence of hypothyroidism on the diagnostic efficacy of different breast imaging techniques. In 2010–2013 the study included 1008 patients: 501 (49.7 %) patients with hypothyroidism and 507 (50.3 %) patients without hypothyroidism.
Mammography and ultrasound with Doppler mapping and qualitative elastography performed. Diagnostic effectiveness of mammography is lower in patients with hypothyroidism, than in patients without hypothyroidism. The combination of mammography and ultrasound with Dop- pler mapping is most effective in patients with hypothyroidism. Qualitative elastography is impractical because of the lack of additional infor- mation compared with Doppler.
About the Authors
S. K. Ternovoy
Department of Radiodiagnosis and Radiotherapy, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
A. B. Abduraimov
Department of Radiodiagnosis and Radiotherapy, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia
Breast X-ray Imaging Room, University Clinical Hospital Two, Clinical Center, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
K. A. Lesko
Department of Radiodiagnosis and Radiotherapy, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia
Breast X-ray Imaging Room, University Clinical Hospital Two, Clinical Center, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
References
1. Злокачественные заболевания в России в 2011 году (заболеваемость и смертность). Под. ред. В.И. Чиссова, В.В. Старинского, Г.В. Петровой. М.: ФГБУ МНИОИ им. П.А. Герцена Минздрава России, 2013. 289 с.
2. Бурдина Л.М. Дисгормональные гиперплазии молочных желез – особенности развития, дифференциальная диагностика. Радиол практика 2007;(3):44–61.
3. Тагиева Т.Т. Фиброзно-кистозная мастопатия. Гинекология 2005;7(3):141–4.
4. Assi V., Warwick J., Cuzick J., Duffy S.W. Clinical and epidemiological issues in mammographic density. Nat Rev Clin Oncol 2011;9(1):33–40.
5. Yaffe M.J. Measurement of mammographic density. http://breast-cancer-research.com/ content/10/3/209.
6. Клиническая маммология (практическое руководство). Под ред. М.И. Давыдова, В.П. Летягина. М.: АБВ- пресс, 2010. С. 54–6.
7. Кроненберг Г.М., Мелмед Ш., Полон- ски К.С., Ларсен П.Р. Заболевания щитовидной железы. Пер. с англ. под ред. И.И. Дедова, Г.А. Мельниченко. М.: ООО «Рид Элсивер», 2010. С. 215–96.
8. Прилепская В.Н., Волобуев А.И., Швецова О.Б. Масталгия у женщин репродуктивного возраста: клиника, диагностика, лечение. Гинекология 2003;5(4):20–4.
9. Martinez-Iglesias O., Garcia-Silva S., Regadera J., Aranda A. Hypothyroidism enhances tumor invasiveness and metastasis development. PLoS One 2009;4(7):e6428.
10. Гилязутдинов И.А., Хасанов Р.Ш. Доброкачественные опухоли молочных желез: Руководство для врачей. Казань: Медлите- ратура, 2007. 216 с.
11. Трынченкова Н.Н., Слонимская Е.М., Кравец Е.Б. Влияние тиреоидного статуса на формирование дисгормональных заболеваний молочной железы. Сибирск онкол журн 2005;(4):21–6.
12. Тагиева Т.Т. Доброкачественные заболевания молочных желез у женщин позднего репродуктивного возраста. Гинекология 2001;3(3):107–10.
13. Kuijpens J.L., Nyklictek I., Louwman M.W. et al. Hypothyroidism might be related to breast cancer in post-menopausal women. Thyroid 2005;15(11):1253–9.
14. Hardefeldt P.J., Eslick G.D., Edirimanne S. Benign thyroid disease is associated with breast cancer: a meta-analysis. Breast Cancer Res Treat 2012;133(3):1169–77.
15. Angelousi A.G., Anagnostou V.K., Stamatakos M.K. et al. Primary hypothyroidism and risk for breast cancer: a systematic review and meta-analysis. Eur J Endocrinol 2012;166(3):373–81.
16. Cristofanilli M., Yamamura Y., Kau S.W. et al. Thyroid hormone and breast carcinoma. Primary hypothyroidism is associated with a reduced incidence of primary breast carcinoma. Cancer 2005;103(6):1122–8.
17. Трошина Е.А., Юкина М.Ю. Синдром гипотиреоза. Клиницист 2008;(1):45–50.
18. Фадеев В.В. Современные принципы диагностики и лечения гипотиреоза. Земский врач 2010;(2):13–6.
19. Hollowell J.G., Staehling N.W., Flanders W.D. et al. Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III). J Clin Endocrinol Metab 2002;87(2):489–99.
20. Фишер У., Фридеман Б., Люфтнер- Нагель С. Заболевания молочных желез. Пер. с англ. под общ. ред. чл.-корр. РАМН проф. Б.И. Долгушина. М.: МЕДпресс-ин- форм, 2009. 256 c.
21. Wojcinski S., Boehme E., Farrokh A. et al. Ultrasound real-time elastography can predict malignancy in BI-RADS(R)-US 3 lesions. http://www.biomedcentral.com/1471- 2407/13/159.
22. Sadigh G., Carlos R.C., Neal C.H., Dwamena B.A. Ultrasonographic differentiation of malignant from benign breast lesions: a meta-analytic comparison of elasticity and BIRADS scoring. Breast Cancer Res Treat 2012;133(1):23–35.
23. Itoh A., Ueno E., Tohno E. et al. Breast disease: clinical application of US elastography for diagnosis. Radiology 2006;239(2):341–50.
24. Chiorean A.R., Duma M.M., Dudea S.M. et al. Typical and unusual sonoelastographic patterns of breast cystic lesions: impact on BI- RADS classification. Ultraschall Med 2012;33(7):138–44.
25. Berg W.A., Blume J.D., Cormack J.B. et al. Combined screening with ultrasound and mammography vs mammography alone in women at elevated risk of breast cancer. JAMA 2008;299(18):2151–63.
26. Nothacker M., Duda V., Hahn M. et al. Early detection of breast cancer: benefits and risks of supplemental breast ultrasound in asymptomatic women with mammographically dense breast tissue – a systematic review. http://www.biomedcentral.com/1471- 2407/9/335 (дата обращения 08.05.2013).
27. Özdemir A., Özdemir H., Maral I. et al. Differential diagnosis of solid breast lesions: contribution of Doppler studies to mammography and gray scale imaging. J Ultrasound Med 2001;20(10):1091–101.
28. Hong A.S., Rosen E.L., Soo M.S., Baker J.A. BI-RADS for sonography: positive and negative values of sonographic features. Am J Roentgenol 2005;184(4):1260–5.
29. Cho N., Jang M., Lyou C.Y. Distinguishing benign from malignant masses at breast US: combined US elastography and color doppler US – influence on radiologist accuracy. Radiology 2012;262(1):80–90.
30. Burnside E.S., Hall T.J., Sommer A.M. et al. Differentiating benign from malignant solid breast masses with US strain imaging. Radiology 2007;245(2):401–10.
31. Scaperrotta G., Ferranti C., Costa C. et al. Role of sonoelastography in non-palpable breast lesions. Eur Radiol 2008;18(11):2381–9. 32. Sohn Y.M., Kim M.J., Kim E.K. et al. Sonographic elastography combined with conventional sonography: how much is it helpful for diagnostic performance? J Ultrasound Med 2009;28(4):413–20.
32. Raza S., Odulate A., Ong E.M. et al. Using real-time tissue elastography for breast lesion evaluation: our initial experience. J Ultrasound Med 2010;29(4):551–63.
33. Gong X., Xu Q., Xu Z. et al. Real-time elastography for the differentiation of benign and malignant breast lesions: a meta-analysis. Breast Cancer Res Treat 2011; 130(1):11–8.
34. Kadour M.J., Adams R., English R. et al. Slip imaging: reducing ambiguity in breast lesion assessment. Ultrasound Med Biol 2010;36(12):2027–35.
35. Yoon J.H., Kim M.H., Kim E.K. et al. Interobserver variability of ultrasound elastography: how it affects the diagnosis of breast lesions. Am J Roentgenol 2011;196(3):730–6.
36. Hatzung G., Grunwald S., Zygmunt M. et al. Sonoelastography in the diagnosis of malignant and benign breast lesions: initial clinical experiences. Ultraschall Med 2010;31(6):596–603.
37. Parajuly S.S., Lan P.Y., Yan L. et al. Breast elastography: a hospital-based preliminary study in China. Asian Pac J Cancer Prev 2010;11(3):809–14.
38. Lee J.H., Kim S.H., Kang B.J. et al. Role and clinical usefulness of elastography in small breast masses. Acad Radiol 2011;18(1):74–80.
Review
For citations:
Ternovoy S.K., Abduraimov A.B., Lesko K.A. Breast cancer radiology in women with hypothyroidism. Tumors of female reproductive system. 2013;(3-4):33-40. (In Russ.) https://doi.org/10.17650/1994-4098-2013-0-3-4-33-40
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