Email this article RISK FACTORS FOR MULTIPLE PRIMARY MALIGNANT TUMORS OF THE OVARIES AMONG WOMEN OF THE NOVOSIBIRSK REGION
- Authors: Gerasimov A.V.1,2, Savkova A.V.3, Krasilnikov S.E.1,3, Gulyaeva L.F.3, Voytsitskiy V.E.1, Dudareva A.V.3, Pasman N.M.3
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Affiliations:
- Novosibirsk Regional Clinical Oncology Dispensary
- Research Institute of Molecular Biology and Biophysics
- Novosibirsk State Medical University, Ministry of Health of Russia
- Issue: Vol 13, No 4 (2017)
- Pages: 56-62
- Section: GYNECOLOGY. ORIGINAL REPORTS
- Published: 22.12.2017
- URL: https://ojrs.abvpress.ru/ojrs/article/view/564
- DOI: https://doi.org/10.17650/1994-4098-2017-13-4-56-62
- ID: 564
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Abstract
Background. The problem of multiple primary malignant tumors has recently become particularly important.
Objective: to identify risk factors for multiple primary malignant tumors of the ovaries among women residing in the Novosibirsk region.
Materials and methods. The study included 31 patients with synchronous multiple primary tumors (SMPT), 42 patients with metachronous multiple primary tumors (MMPT) and 160 patients without malignant tumors in anamnesis. We used medical records of these patients to conduct a comparative analysis.
Results and conclusions. Patients with multiple primary malignant tumors (both SMPT and MMPT) were more often engaged in mental work (ꭓ2 = 8.029, р = 0.012), had family history of cancer (ꭓ2 = 10.581, р = 0.001), shorter menstrual cycle (F = 21.082, р = 0.00002) and larger number of abortions (Н = 11.219, р = 0.004) than patients without malignant tumors. Patients with SMPT were more likely to be obese (ꭓ2 = 10.679, p = 0.005), had prolonged menstrual bleeding (F = 3.783, p = 0.024), later menopause (H = 9.832, p = 0.007) and a long reproductive period (H = 8.908, p = 0.012).About the authors
A. V. Gerasimov
Novosibirsk Regional Clinical Oncology Dispensary; Research Institute of Molecular Biology and Biophysics
Author for correspondence.
Email: dr.gerasimov@yandex.ru
2 Plakhotnogo St., Novosibirsk 630108; 2/12 Timakova St., Novosibirsk 630117 Russian Federation
A. V. Savkova
Novosibirsk State Medical University, Ministry of Health of Russia52 Krasnyi Prospekt, Novosibirsk 630091 Russian Federation
S. E. Krasilnikov
Novosibirsk Regional Clinical Oncology Dispensary; Novosibirsk State Medical University, Ministry of Health of Russia2 Plakhotnogo St., Novosibirsk 630108; 52 Krasnyi Prospekt, Novosibirsk 630091 Russian Federation
L. F. Gulyaeva
Novosibirsk State Medical University, Ministry of Health of Russia52 Krasnyi Prospekt, Novosibirsk 630091 Russian Federation
V. E. Voytsitskiy
Novosibirsk Regional Clinical Oncology Dispensary2 Plakhotnogo St., Novosibirsk 630108 Russian Federation
A. V. Dudareva
Novosibirsk State Medical University, Ministry of Health of Russia52 Krasnyi Prospekt, Novosibirsk 630091 Russian Federation
N. M. Pasman
Novosibirsk State Medical University, Ministry of Health of Russia52 Krasnyi Prospekt, Novosibirsk 630091 Russian Federation
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