RISK FACTORS FOR MULTIPLE PRIMARY MALIGNANT TUMORS OF THE OVARIES AMONG WOMEN OF THE NOVOSIBIRSK REGION
https://doi.org/10.17650/1994-4098-2017-13-4-56-62
Abstract
Background. The problem of multiple primary malignant tumors has recently become particularly important.
Objective: to identify risk factors for multiple primary malignant tumors of the ovaries among women residing in the Novosibirsk region.
Materials and methods. The study included 31 patients with synchronous multiple primary tumors (SMPT), 42 patients with metachronous multiple primary tumors (MMPT) and 160 patients without malignant tumors in anamnesis. We used medical records of these patients to conduct a comparative analysis.
Results and conclusions. Patients with multiple primary malignant tumors (both SMPT and MMPT) were more often engaged in mental work (ꭓ2 = 8.029, р = 0.012), had family history of cancer (ꭓ2 = 10.581, р = 0.001), shorter menstrual cycle (F = 21.082, р = 0.00002) and larger number of abortions (Н = 11.219, р = 0.004) than patients without malignant tumors. Patients with SMPT were more likely to be obese (ꭓ2 = 10.679, p = 0.005), had prolonged menstrual bleeding (F = 3.783, p = 0.024), later menopause (H = 9.832, p = 0.007) and a long reproductive period (H = 8.908, p = 0.012).About the Authors
A. V. Gerasimov
Novosibirsk Regional Clinical Oncology Dispensary; Research Institute of Molecular Biology and Biophysics
Russian Federation
2 Plakhotnogo St., Novosibirsk 630108; 2/12 Timakova St., Novosibirsk 630117
Russian Federation
2 Plakhotnogo St., Novosibirsk 630108; 2/12 Timakova St., Novosibirsk 630117
A. V. Savkova
Novosibirsk State Medical University, Ministry of Health of Russia
Russian Federation
52 Krasnyi Prospekt, Novosibirsk 630091
Russian Federation
52 Krasnyi Prospekt, Novosibirsk 630091
S. E. Krasilnikov
Novosibirsk Regional Clinical Oncology Dispensary; Novosibirsk State Medical University, Ministry of Health of Russia
Russian Federation
2 Plakhotnogo St., Novosibirsk 630108; 52 Krasnyi Prospekt, Novosibirsk 630091
Russian Federation
2 Plakhotnogo St., Novosibirsk 630108; 52 Krasnyi Prospekt, Novosibirsk 630091
L. F. Gulyaeva
Novosibirsk State Medical University, Ministry of Health of Russia
Russian Federation
52 Krasnyi Prospekt, Novosibirsk 630091
Russian Federation
52 Krasnyi Prospekt, Novosibirsk 630091
V. E. Voytsitskiy
Novosibirsk Regional Clinical Oncology Dispensary
Russian Federation
2 Plakhotnogo St., Novosibirsk 630108
Russian Federation
2 Plakhotnogo St., Novosibirsk 630108
A. V. Dudareva
Novosibirsk State Medical University, Ministry of Health of Russia
Russian Federation
52 Krasnyi Prospekt, Novosibirsk 630091
Russian Federation
52 Krasnyi Prospekt, Novosibirsk 630091
N. M. Pasman
Novosibirsk State Medical University, Ministry of Health of Russia
Russian Federation
52 Krasnyi Prospekt, Novosibirsk 630091
Russian Federation
52 Krasnyi Prospekt, Novosibirsk 630091
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Review
For citations:
Gerasimov A.V., Savkova A.V., Krasilnikov S.E., Gulyaeva L.F., Voytsitskiy V.E., Dudareva A.V., Pasman N.M. RISK FACTORS FOR MULTIPLE PRIMARY MALIGNANT TUMORS OF THE OVARIES AMONG WOMEN OF THE NOVOSIBIRSK REGION. Tumors of female reproductive system. 2017;13(4):56-62. (In Russ.) https://doi.org/10.17650/1994-4098-2017-13-4-56-62
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