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Individual approach to choosing an appropriate regimen of adjuvant hormone therapy in patients with early-stage breast cancer
- Authors: Slonimskaya E.M.1, Doroshenko A.V.1, Kazantseva P.V.1, Tarabanovskaya N.A.1, Vernadsky R.Y.1
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Affiliations:
- Oncology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences
- Issue: Vol 14, No 3 (2018)
- Pages: 48-54
- Section: MAMMOLOGY. REVIEWS
- Published: 15.10.2018
- URL: https://ojrs.abvpress.ru/ojrs/article/view/606
- DOI: https://doi.org/10.17650/1994-4098-2018-14-3-48-54
- ID: 606
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Abstract
Adjuvant hormone therapy is considered the gold standard of therapy for hormone receptor-positive operable breast cancer. The approach to adjuvant hormone therapy in premenopausal patients has changed significantly in recent years. This change was caused by clinical trials, which have confirmed the advantage of adding ovarian suppression to tamoxifen or aromatase inhibitors monotherapy. Individual approach to choosing an appropriate regimen of adjuvant hormone therapy in premenopausal patients with breast cancer should be based on the assessment of risks for relapse, expected effectiveness of treatment and evaluation of drug safety.
About the authors
E. M. Slonimskaya
Oncology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences
Author for correspondence.
Email: slonimskaya@rambler.ru
ORCID iD: 0000-0003-4382-5697
5 Kooperativniy per., Tomsk 634050
Russian Federation
A. V. Doroshenko
Oncology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences
ORCID iD: 0000-0001-8846-9636
5 Kooperativniy per., Tomsk 634050
Russian Federation
P. V. Kazantseva
Oncology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences
ORCID iD: 0000-0002-2953-0350
5 Kooperativniy per., Tomsk 634050
Russian Federation
N. A. Tarabanovskaya
Oncology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences
ORCID iD: 0000-0003-1630-4466
5 Kooperativniy per., Tomsk 634050
Russian Federation
R. Yu. Vernadsky
Oncology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences
5 Kooperativniy per., Tomsk 634050
Russian Federation
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