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Tumor markers in the diagnosis of cancer of the corpus uteri (a review of literature)

https://doi.org/10.17650/1994-4098-2013-0-3-4-67-71

Abstract

Towards the end of the past century, cancer of the corpus uteri achieved the status of leading gynecologic cancer not only in developed countries, but also in Third World countries. The leading determinants of prognosis and treatment policy are tumor extent and grade at diagnosis. It is important to search for the informative and significant indicators of biological tumor activity, which are determined by pre- and postoperative mini-invasive laboratory studies, the combination of which could additionally judge the extent and grade of a tumor. At present, there are no significant tumor markers for the screening for and evaluation of progressive cancer of the corpus uteri, which would have a high specificity and sensitivity although their search is constantly underway worldwide.

About the Authors

D. B. Olkin
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation


L. I. Bokina
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation


E. A. Mustafina
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation


V. V. Barinov
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation


I. I. Bokin
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation


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Review

For citations:


Olkin D.B., Bokina L.I., Mustafina E.A., Barinov V.V., Bokin I.I. Tumor markers in the diagnosis of cancer of the corpus uteri (a review of literature). Tumors of female reproductive system. 2013;(3-4):67-71. (In Russ.) https://doi.org/10.17650/1994-4098-2013-0-3-4-67-71

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ISSN 1994-4098 (Print)
ISSN 1999-8627 (Online)