Ведущая роль топотекана в лечении платинорезистентных рецидивов рака яичников
https://doi.org/10.17650/1994-4098-2012-0-1-102-112
Аннотация
В обзоре представлены данные об эффективности применения ингибитора топоизомеразы I топотекана у больных с рецидивами рака яичников в сравнении с другими химиотерапевтическими агентами. Показано, что топотекан может быть препаратом выбора при платинорезистентных рецидивах. Для уменьшения степени гематологической токсичности рекомендовано ежене- дельное введение препарата в дозе 4 мг/м2 в 1, 8, 15-й дни 28-дневного цикла терапии, эффективность которого сопоставима с эффективностью стандартного 5-дневного режима.
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Рецензия
Для цитирования:
Борисов К.Е. Ведущая роль топотекана в лечении платинорезистентных рецидивов рака яичников. Опухоли женской репродуктивной системы. 2012;(1):102-112. https://doi.org/10.17650/1994-4098-2012-0-1-102-112
For citation:
Borisov K.E. The leadership of topotecan in the treatment of recurrent platinum-resistant ovarian cancer. Tumors of female reproductive system. 2012;(1):102-112. (In Russ.) https://doi.org/10.17650/1994-4098-2012-0-1-102-112
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