Аспекты выбора первичного лечения больных распространенным раком яичников
Аннотация
В статье рассмотрены вопросы выбора тактики лечения пациенток с диссеминированными формами рака яичников. Подробно оценена современная доказательная база, касающаяся преимуществ и недостатков выполнения хирургического лечения или неоадъювантной химиотерапии на 1-м этапе лечения в зависимости от функционального состояния больных и распространенности опухолевого процесса. Представлены данные литературы о частоте оптимальных циторедукций в различных странах мира и выживаемости больных в зависимости от размера остаточной опухоли после хирургического этапа лечения. Рассмотрена роль вы- полнения лимфодиссекции, а также комбинированных хирургических операций с резекцией тонкой и/или толстой кишки, печени, селезенки, брюшины и т.д. Проанализированы существующие факторы прогноза и прогностические модели, позволяющие выделить пациенток, которым на 1-м этапе лечения в силу низкой вероятности выполнения оптимальной циторедукции показано проведение неоадъювантной химиотерапии.
Об авторах
С. О. Никогосян
ФГБУ «РОНЦ им. Н.Н. Блохина» Минздрава России
Россия
Россия
гинекологическое отделение,
115478, Москва, Каширское шоссе, 23
В. В. Кузнецов
ФГБУ «РОНЦ им. Н.Н. Блохина» Минздрава России
Россия
Россия
гинекологическое отделение,
115478, Москва, Каширское шоссе, 23
А. З. Загаштоков
ФГБУ «РОНЦ им. Н.Н. Блохина» Минздрава России
Россия
Россия
гинекологическое отделение,
115478, Москва, Каширское шоссе, 23
А. А. Румянцев
ФГБУ «РОНЦ им. Н.Н. Блохина» Минздрава России
Россия
Россия
гинекологическое отделение,
115478, Москва, Каширское шоссе, 23
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Для цитирования:
Никогосян С.О., Кузнецов В.В., Загаштоков А.З., Румянцев А.А. Аспекты выбора первичного лечения больных распространенным раком яичников. Опухоли женской репродуктивной системы. 2016;12(3):62-69. https://doi.org/10.17650/1994-4098-2016-12-3-62-69
For citation:
Nikogosyan S.O., Kuznetsov V.V., Zagashtokov A.Z., Rumyantsev A.A. Optimizing the primary treatment of patients with advanced ovarian cancer. Tumors of female reproductive system. 2016;12(3):62-69. (In Russ.) https://doi.org/10.17650/1994-4098-2016-12-3-62-69
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